This is a collection of autograph letters, principally to Hosack, but also between other correspondents.

These papers include diaries (1777-1782), expense books (1794-1804), notebooks, a commonplace book, drafts of essays, excerpts from minutes of Friends' Monthly Meeting, Tortola (1741-1761), newspaper clippings, sketches, and correspondence. Also included are letters and papers of Mrs. Thornton.

This item is a daily record of professional visits and prescriptions. Some of Shippen's patients were eminent Philadelphians and visitors to the city.